Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | PTGIR | P43119 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103904 | 0.87 | MAOB (0.61) | MAOBMAOAMAPTMEN1KMT2A | |
| 1,4-Dimethoxybenzene SCHEMBL28617696 | 0.87 | MAOB (0.61) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL30757515 | 0.87 | MAOB (0.61) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL30250275 | 0.85 | MAOA (0.59) | MAOBMAOAMEN1KMT2ACA12 | |
| SCHEMBL7288433 | 0.83 | HTR2C (0.51) | MAOBMAOAPTGIRMAPTMEN1 | |
| SCHEMBL920849 | 0.83 | MAOA (0.58) | MAOBMAOAPTGIRGSK3B | |
| SCHEMBL482369 | 0.82 | CA1 (0.65) | PTGIRMAPTMEN1KMT2ACA12 | |
| SCHEMBL3394075 | 0.82 | MAOB (0.81) | MAOBMAOACA12CA2CA9 | |
| SCHEMBL3419967 | 0.81 | MAOA (0.56) | MAOBMAOAMAPTMEN1KMT2A | |
| SCHEMBL921496 | 0.81 | MAOA (0.56) | MAOBMAOAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108347936-B | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| US-20210070779-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS INC (US) | 2021-03-11 | — | — | US | disclosed |
| US-20210070779-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS INC (US) | 2021-03-11 | — | — | US | disclosed |
| US-20200207789-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS INC (US) | 2020-07-02 | — | — | US | disclosed |
| US-20200207789-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS INC (US) | 2020-07-02 | — | — | US | disclosed |
| US-20180319753-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-08 | — | — | US | disclosed |
| US-20180291040-A1 | Boron-Containing Small Molecules As Anti-Inflammatory Agents | ANACOR PHARMACEUTICALS INC (US) | 2018-10-11 | — | — | US | disclosed |
| EP-3367798-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-09-05 | — | — | EP | disclosed |
| CN-108347936-A | Kill microorganism oxadiazole derivatives | 先正达参股股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017072247-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-04 | — | — | WO | disclosed |
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| CN-1035001-C | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1997-05-28 | — | — | CN | disclosed |
| EP-0451007-B1 | Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy | FOURNIER IND & SANTE (FR) | 1995-11-08 | — | — | EP | disclosed |
| CN-1088906-A | The phenyl phenol leukotriene antagonists that replaces | LILLY CO ELI (US) | 1994-07-06 | — | — | CN | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| EP-0271195-B1 | SUBSTITUTED TRIAZINE DERIVATIVES | Horsell Plc (GB) | 1992-04-22 | — | — | EP | disclosed |
| US-5100913-A | Venous antithrombotics | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-03-31 | — | — | US | disclosed |
| EP-0451007-A1 | Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1991-10-09 | — | — | EP | disclosed |
| US-4912218-A | Substituted triazine derivatives | COOKSON GROUP PLC (GB) | 1990-03-27 | — | — | US | disclosed |
| EP-0271195-A1 | Substituted triazine derivatives | Horsell Plc (GB) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070779-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, TNF, LITAF | MAOB 887/4885MAOA 2800/4885PTGIR 490/4885 |
| US-20200207789-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, TNF, LITAF | MAOB 887/4885MAOA 2800/4885PTGIR 490/4885 |
| US-20180291040-A1 | Boron-Containing Small Molecules As Anti-Inflammatory Agents | NFKBIA, TNF, LITAF | MAOB 887/4885MAOA 2800/4885PTGIR 490/4885 |
| US-20180319753-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | MAOB 1078/4885MAOA 866/4885PTGIR 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.