Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 5/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568782 | 0.86 | ALPG (0.54) | CTSDL3MBTL1 | |
| SCHEMBL8865006 | 0.80 | F2R (0.59) | KMT2A | |
| SCHEMBL8567175 | 0.77 | POLB (0.55) | RAB9AALDH1A1NPC1KDM4EHPGD | |
| SCHEMBL8568760 | 0.75 | MAPT (0.56) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL21912954 | 0.70 | GABRA5 (0.44) | RAB9AALDH1A1NPC1KDM4EHPGD | |
| Bromide SCHEMBL6746472 | 0.66 | MAPT (0.72) | RAB9ACXCR3ALDH1A1NPC1KDM4E | |
| SCHEMBL13979176 | 0.62 | CYP19A1 (0.74) | L3MBTL1 | |
| SCHEMBL21325569 | 0.62 | DDB1 (0.44) | ALDH1A1KDM4EHPGD | |
| SCHEMBL14373251 | 0.61 | CXCR3 (0.81) | RAB9ACXCR3NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL11256989 | 0.60 | APEX1 (0.79) | RAB9AALDH1A1NPC1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |