SCHEMBL8568782

SCHEMBL8568782

O=C(Cn1c2ccccc2n2ccnc12)c1ccc(O)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALPG P10696 14/20 0.54
ALPL P05186 11/20 0.54
PLAA Q9Y263 10/20 0.54
ALPP P05187 1/20 0.54
CTSD P07339 1/20 0.54
ALPI P09923 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
GFER P55789 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8568517 0.86 CTSD (0.41) CTSDL3MBTL1
SCHEMBL8865006 0.79 F2R (0.59)
SCHEMBL8567175 0.74 POLB (0.55)
SCHEMBL8568760 0.72 MAPT (0.56)
SCHEMBL21912954 0.68 GABRA5 (0.44) TDP1L3MBTL1
Hydrochloric Acid SCHEMBL31091232 0.66 ALPG (1.00) ALPGALPLPLAAALPITDP1
Hydrochloric Acid SCHEMBL11363673 0.64 ALPG (1.00) ALPGALPLPLAAALPITDP1
SCHEMBL20276983 0.61 MAPT (0.68) PLAA
SCHEMBL18805093 0.61 ALPG (0.65) ALPGALPLPLAAALPITDP1
Hydrochloric Acid SCHEMBL29873211 0.61 LMNA (0.64) ALPGALPLPLAAALPITDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571253-B1 Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity ADIR (FR) 1998-11-04 EP disclosed
US-5639756-A ANTIDIABETIC AGENTS ADIR ET COMPAGNIE (FR) 1997-06-17 US disclosed
EP-0571253-A1 Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity ADIR ET COMPAGNIE (FR) 1993-11-24 EP disclosed