Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070995 | 0.89 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTHPGDALOX15 | |
| SCHEMBL8062512 | 0.88 | P4HB (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL8078064 | 0.84 | TOP2A (0.38) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL8063153 | 0.84 | TOP2A (0.38) | — | |
| SCHEMBL8076213 | 0.83 | CSNK2A2 (0.37) | ALDH1A1LMNAMAPTHPGDTSHR | |
| SCHEMBL8072589 | 0.82 | TNF (0.43) | MEN1KMT2A | |
| SCHEMBL8078076 | 0.82 | MEN1 (0.41) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8427333 | 0.78 | CES2 (0.36) | — | |
| SCHEMBL8070987 | 0.77 | ELANE (0.38) | MEN1KMT2A | |
| SCHEMBL8073319 | 0.75 | SLC37A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5844004-A | 10-substituted 1,8-dihydroxy-9 (10H) anthracenone pharmaceuticals | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1998-12-01 | — | — | US | disclosed |