Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425196 | 0.86 | CES2 (0.38) | CES2 | |
| SCHEMBL8425316 | 0.85 | CES2 (0.39) | CES2 | |
| SCHEMBL8427351 | 0.79 | P4HB (0.39) | — | |
| SCHEMBL8569420 | 0.78 | EPHX1 (0.38) | — | |
| SCHEMBL8070987 | 0.72 | ELANE (0.38) | — | |
| SCHEMBL8569425 | 0.70 | MEN1 (0.48) | — | |
| SCHEMBL8073319 | 0.70 | SLC37A4 (0.36) | — | |
| SCHEMBL9186283 | 0.69 | MAPT (0.49) | — | |
| SCHEMBL8062545 | 0.69 | ACHE (0.36) | — | |
| SCHEMBL8427797 | 0.68 | HDAC4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952390-A | ANTIINFLAMMATORY AGENTS; TREATMENT FOR PSORIASIS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1999-09-14 | — | — | US | disclosed |