Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 3/20 | 0.31 |
| ▸ | RARB | P10826 | 3/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570979 | 0.87 | EPHX2 (0.40) | EPHX2P2RX7CNR2KMT2AALDH1A1 | |
| SCHEMBL8569800 | 0.70 | FFAR1 (0.35) | EPHX2P2RX7MAPTRARARARB | |
| SCHEMBL8569797 | 0.69 | RARA (0.46) | EPHX2MAPTGAARARARARB | |
| SCHEMBL8571816 | 0.68 | EPHX2 (0.40) | EPHX2P2RX7CNR2KMT2AALDH1A1 | |
| SCHEMBL20178896 | 0.67 | RARA (0.48) | EPHX2MAPTGAACNR2RARA | |
| SCHEMBL2709569 | 0.65 | HIF1A (0.46) | EPHX2MAPTGAARARARARB | |
| SCHEMBL2709267 | 0.65 | HIF1A (0.46) | EPHX2NPC1MEN1KMT2AKDM4E | |
| SCHEMBL8570976 | 0.65 | KMT2A (0.49) | CNR2RARARARBRARGIKBKB | |
| SCHEMBL8570978 | 0.64 | MEN1 (0.37) | EPHX2CNR2RARARARBRARG | |
| SCHEMBL8567757 | 0.63 | HNF4A (0.46) | EPHX2P2RX7MAPTGAARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |