Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563757 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL8566551 | 0.84 | ALDH1A1 (0.46) | MAPK1ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL8566844 | 0.79 | MEN1 (0.40) | ALDH1A1MAPTTDP1KMT2AALOX15 | |
| SCHEMBL8562112 | 0.76 | GAA (0.41) | MAPK1ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL2646463 | 0.74 | ALDH1A1 (0.42) | MAPK1ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL12661517 | 0.74 | KDM4E (0.39) | MAPK1ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL8599704 | 0.73 | ALDH1A1 (0.50) | MAPK1ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL8597868 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AL3MBTL1ALOX15 | |
| SCHEMBL8568707 | 0.73 | CES2 (0.39) | ALDH1A1MAPTPOLBHTTSMN1; SMN2 | |
| SCHEMBL8600107 | 0.72 | KDM4E (0.36) | ALDH1A1KDM4EHPGDCYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |