Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27353376 | 0.84 | MAOA (0.42) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL10265067 | 0.84 | MAOA (0.52) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL3489922 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL2291350 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL21215541 | 0.80 | MAOA (0.40) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL10205344 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL2292509 | 0.78 | ALPL (0.44) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL329996 | 0.78 | MAOA (0.41) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL29446704 | 0.78 | MAOA (0.41) | KDM4EALDH1A1HPGDLMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL629298 | 0.77 | L3MBTL1 (0.41) | KDM4EALDH1A1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830912-A | Derivatives of 6,8-difluoro-7-hydroxycoumarin | MOLECULAR PROBES, INC. (US) | 1998-11-03 | — | — | US | disclosed |