SCHEMBL2291350

SCHEMBL2291350

CCCC(=O)Oc1c(F)cc2c(C)cc(=O)oc2c1F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.51
ALDH1A1 P00352 7/20 0.51
GAA P10253 6/20 0.51
KMT2A Q03164 6/20 0.51
GLA P06280 3/20 0.51
LMNA P02545 4/20 0.51
HTT P42858 3/20 0.51
HSD17B10 Q99714 4/20 0.45
HPGD P15428 3/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 5/20 0.42
PAX8 Q06710 1/20 0.42
UBE2N P61088 1/20 0.41
TP53 P04637 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
MCL1 Q07820 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513173 0.92 LMNA (0.47) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL8570332 0.80 KDM4E (0.57) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL10265067 0.78 MAOA (0.52) KDM4EALDH1A1GAAKMT2ALMNA
SCHEMBL12987943 0.76 KDM4E (0.65) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL2292509 0.75 ALPL (0.44) KDM4EALDH1A1GAALMNAHTT
SCHEMBL329996 0.75 MAOA (0.41) KDM4EALDH1A1GAALMNAHTT
SCHEMBL29446704 0.75 MAOA (0.41) KDM4EALDH1A1GAALMNAHTT
SCHEMBL21215541 0.75 MAOA (0.40) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL10205344 0.75 KDM4E (0.46) KDM4EALDH1A1GAAGLALMNA
Ammonia Solution, Strong SCHEMBL629298 0.74 L3MBTL1 (0.41) KDM4EALDH1A1GAAKMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9631219-B2 Metabolic rate indicator for cellular populations NALCO COMPANY (US) 2017-04-25 US claimed
US-9631219-B2 Metabolic rate indicator for cellular populations NALCO COMPANY (US) 2017-04-25 US disclosed
WO-2011106363-A2 METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS NALCO COMPANY (US) 2011-09-01 WO disclosed
US-20110207111-A1 METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS ECOLAB USA INC. 2011-08-25 US disclosed