Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.72 |
| ▸ | MMP13 | P45452 | 8/20 | 0.70 |
| ▸ | MMP2 | P08253 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | MMP14 | P50281 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994860 | 1.00 | RAB9A (1.00) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31310280 | 0.90 | RAB9A (0.81) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5623372 | 0.88 | KDM4E (0.78) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31310346 | 0.87 | ALDH1A1 (0.77) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL68923 | 0.86 | HRH3 (0.84) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL829213 | 0.86 | KDM4E (0.76) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL829242 | 0.86 | KDM4E (0.76) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8870168 | 0.86 | KDM4E (0.75) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31310255 | 0.86 | RAB9A (0.75) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL940171 | 0.85 | KDM4E (0.74) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831275-A | Indole-substituted 6-phenylindenoindole derivative and preparation method and application thereof | 上海兆维科技发展有限公司 | 2021-12-24 | — | — | CN | claimed |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | claimed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | claimed |
| CN-104030971-B | A kind of method synthesizing carbazole alkaloid karapinchamine A | 浙江大学 | 2016-12-07 | — | — | CN | claimed |
| CN-104030971-A | Method for synthesizing carbazole alkaloid karapinchamine A | UNIV ZHEJIANG | 2014-09-10 | — | — | CN | claimed |
| US-12570679-B2 | STAT3 protein degraders | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2026-03-10 | — | — | US | disclosed |
| US-12522623-B2 | Small molecule STAT protein degraders | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2026-01-13 | — | — | US | disclosed |
| EP-4634156-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-10-22 | — | — | EP | disclosed |
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-26 | — | — | US | disclosed |
| US-12168009-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-12-17 | — | — | US | disclosed |
| WO-2024238598-A2 | STAT DEGRADERS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| WO-2024125624-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-06-20 | — | — | WO | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |
| EP-1003504-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | AstraZeneca UK Limited (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007351-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ZENECA LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |
| US-5440046-A | Angiotensin antagonist, hypotensive agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| US-5428043-A | Tricyclic-cyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-5350751-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-27 | — | — | US | disclosed |
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4137313-A | ANTICOAGULANTS, ANTIPHLOGISTIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | XPA, MEP1A, EED | RAB9A 3179/4885KDM4E 280/4885ALDH1A1 107/4885 |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | XPA, MEP1A, EED | RAB9A 3179/4885KDM4E 280/4885ALDH1A1 107/4885 |
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | RAB9A 888/4885KDM4E 2973/4885ALDH1A1 3524/4885 |
| US-12570679-B2 | STAT3 protein degraders | STAT3, JAK2, IL6ST | RAB9A 988/4885KDM4E 251/4885ALDH1A1 1666/4885 |
| US-12168009-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | CFTR, SCNN1B, SLC26A4 | RAB9A 888/4885KDM4E 2973/4885ALDH1A1 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.