SCHEMBL8570659

SCHEMBL8570659

CC[N+](Cc1ccccc1)(Cc1ccccc1)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
PKM P14618 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CHRM2 P08172 1/20 0.37
CYP2D6 P10635 1/20 0.37
CHRM1 P11229 1/20 0.37
KCNH2 Q12809 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
EPHX2 P34913 1/20 0.37
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
DNM1 Q05193 1/20 0.35
SLC18A3 Q16572 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569478 0.96 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1L3MBTL1PKM
SCHEMBL8569325 0.88 DNM1 (0.43) ALDH1A1KDM4ETDP1L3MBTL1PKM
SCHEMBL2464746 0.78 ALDH1A1 (0.47) ALDH1A1KDM4ETDP1L3MBTL1PKM
SCHEMBL18886610 0.78 KDM4E (0.47) ALDH1A1KDM4ETDP1L3MBTL1USP2
SCHEMBL7548952 0.77 PKM (0.37) ALDH1A1KDM4EL3MBTL1PKMCTDSP1
Hydrochloric Acid SCHEMBL10658965 0.76 KDM4E (0.50) ALDH1A1KDM4ETDP1L3MBTL1PKM
Iodide SCHEMBL9713862 0.76 CHRNA7 (0.47) ALDH1A1KDM4ETDP1L3MBTL1PKM
Bromide SCHEMBL11405069 0.76 KDM4E (0.45) ALDH1A1KDM4ETDP1USP2HPGD
SCHEMBL9242506 0.75 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1L3MBTL1PKM
Hydrochloric Acid SCHEMBL11599165 0.75 KDM4E (0.48) ALDH1A1KDM4ETDP1USP2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1037175-C Halomethylbenzoyl cyanides and process for preparing same BASF AG (DE) 1998-01-28 CN disclosed
US-5705674-A Process for preparing ortho-nitrobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-06 US disclosed
EP-0619300-B1 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF AG (DE) 1996-12-27 EP disclosed
US-5510528-A Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5446199-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AKTIENGESELLSCHAFT (DE) 1995-08-29 US disclosed
CN-1097412-A Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides BASF AG (DE) 1995-01-18 CN disclosed
EP-0619300-A2 Process for the preparation of halogenmethylbenzoyl cyanides and halogenmethyl benzoylcyanides BASF Aktiengesellschaft (DE) 1994-10-12 EP disclosed