Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575278 | 0.88 | ADORA3 (0.51) | ADORA3NPC1RXFP1TSHRMAPT | |
| SCHEMBL8566680 | 0.81 | NPSR1 (0.60) | ADORA3NPC1RXFP1MAPTALDH1A1 | |
| SCHEMBL8570794 | 0.78 | ADORA3 (0.62) | ADORA3NPC1RXFP1ALDH1A1KDM4E | |
| SCHEMBL8565133 | 0.76 | ALDH1A1 (0.61) | ADORA3NPC1RXFP1TSHRMAPT | |
| SCHEMBL8570862 | 0.76 | ADORA3 (0.59) | ADORA3NPC1RXFP1ALDH1A1KDM4E | |
| SCHEMBL30911334 | 0.74 | ADORA3 (0.61) | ADORA3NPC1RXFP1MAPTKDM4E | |
| SCHEMBL1377141 | 0.73 | ADORA3 (0.68) | ADORA3NPC1RXFP1MAPTRAB9A | |
| SCHEMBL8573144 | 0.72 | ADORA3 (0.62) | ADORA3NPC1RXFP1MAPTRAB9A | |
| SCHEMBL29530821 | 0.70 | ADORA3 (1.00) | ADORA3NPC1RXFP1MAPTHTT | |
| SCHEMBL8566729 | 0.68 | ADORA3 (0.53) | ADORA3NPC1RXFP1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |