Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573273 | 0.92 | ALOX5 (0.35) | MAOAMAPTALOX5ESR1ESR2 | |
| SCHEMBL8578127 | 0.86 | GABRA1 (0.39) | ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL9195092 | 0.81 | TYR (0.39) | TYRMAOAALDH1A1GAAKDM4E | |
| SCHEMBL8579130 | 0.81 | EGFR (0.40) | TYRMAOAALDH1A1GAAKDM4E | |
| SCHEMBL7515172 | 0.79 | TYR (0.40) | TYRTLR8ALDH1A1GAAKDM4E | |
| SCHEMBL27496913 | 0.78 | ALOX5 (0.37) | ALDH1A1GAAKDM4ECYP3A4MAPT | |
| SCHEMBL5692247 | 0.78 | TYR (0.37) | TYRTLR8MAOAALDH1A1GAA | |
| SCHEMBL9193484 | 0.77 | TYR (0.38) | TYRMAOAALDH1A1GAAKDM4E | |
| SCHEMBL8574791 | 0.77 | MEN1 (0.44) | ALDH1A1MAPTALOX5PTGS2ESR1 | |
| SCHEMBL9007350 | 0.76 | ALOX5 (0.39) | TYRMAOACYP3A4MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |