Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195092 | 0.90 | TYR (0.39) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL8573280 | 0.90 | DHFR (0.35) | EGFRALOX5MAOAESR1ESR2 | |
| SCHEMBL9193484 | 0.85 | TYR (0.38) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL9007350 | 0.84 | ALOX5 (0.39) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL9188546 | 0.84 | TYR (0.37) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL27516165 | 0.83 | TYR (0.42) | TYRALOX5HTTALDH1A1MEN1 | |
| SCHEMBL8575917 | 0.82 | GABRA1 (0.39) | HTTALDH1A1MAPTCYP3A4HPGD | |
| SCHEMBL8573285 | 0.81 | TYR (0.36) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL14818255 | 0.79 | ALOX5 (0.42) | EGFRTYRALOX5PTGS2HTT | |
| SCHEMBL9193207 | 0.79 | DHFR (0.35) | ALOX5MAOAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |