Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573285 | 0.92 | TYR (0.36) | ALOX5MAPTESR1ESR2MAOA | |
| SCHEMBL8578127 | 0.88 | GABRA1 (0.39) | MAPTESR1ESR2SMN1; SMN2NPC1 | |
| SCHEMBL27496913 | 0.86 | ALOX5 (0.37) | ALOX5MAPTESR1ESR2NPC1 | |
| SCHEMBL8573280 | 0.80 | DHFR (0.35) | ALOX5ESR1ESR2DHFRMAOA | |
| SCHEMBL9193207 | 0.80 | DHFR (0.35) | ALOX5ESR1ESR2DHFRMAOA | |
| SCHEMBL8574791 | 0.79 | MEN1 (0.44) | ALOX5MAPTESR1ESR2NPC1 | |
| SCHEMBL7521976 | 0.78 | ESR1 (0.36) | ALOX5MAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL27515457 | 0.77 | ESR1 (0.37) | MAPTESR1ESR2 | |
| SCHEMBL5692097 | 0.77 | ALOX5 (0.39) | ALOX5MAPTESR1ESR2SMN1; SMN2 | |
| SCHEMBL8580208 | 0.75 | GABRA1 (0.42) | ALOX5MAPTGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |