Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712010 | 0.82 | CYP1A1 (0.38) | HRH3SLC18A3 | |
| SCHEMBL8707234 | 0.81 | HRH3 (0.37) | HRH3 | |
| SCHEMBL8575385 | 0.79 | CHRNA7 (0.33) | CHRNA7 | |
| SCHEMBL8920052 | 0.78 | KMT2A (0.53) | ALDH1A1SLC18A3L3MBTL1 | |
| SCHEMBL8921220 | 0.77 | MCHR1 (0.30) | — | |
| SCHEMBL8705669 | 0.76 | ACACB (0.39) | ALDH1A1HRH3 | |
| SCHEMBL8921686 | 0.75 | MEN1 (0.38) | ALDH1A1SLC18A3 | |
| SCHEMBL8574139 | 0.74 | CHRNA7 (0.50) | CHRNA7 | |
| SCHEMBL8421972 | 0.74 | ACACB (0.38) | HRH3 | |
| SCHEMBL8417738 | 0.74 | ACACB (0.34) | ALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |