Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572725 | 0.88 | LCK (0.56) | MAPTKDM4ENPSR1TSHRGLA | |
| SCHEMBL8576457 | 0.85 | CA2 (0.51) | GAAKDM4ENPSR1LCKFYN | |
| SCHEMBL29385230 | 0.84 | GAA (0.42) | GAAKDM4ENPSR1TSHRGLA | |
| SCHEMBL22499513 | 0.84 | GAA (0.42) | GAAKDM4ENPSR1TSHRGLA | |
| SCHEMBL8572895 | 0.84 | LMNA (0.45) | MAPTNPSR1TSHRGLAL3MBTL1 | |
| SCHEMBL8572740 | 0.81 | GSTO1 (0.42) | MAPTKDM4ETSHRL3MBTL1GSTO1 | |
| SCHEMBL8574456 | 0.79 | GSTO1 (0.40) | MAPTTSHRL3MBTL1GSTO1KMT2A | |
| SCHEMBL8571655 | 0.79 | GSTO1 (0.38) | MAPTNPSR1TSHRL3MBTL1GSTO1 | |
| SCHEMBL8574663 | 0.78 | VCAM1 (0.44) | GAAKDM4EHTTGSTO1MEN1 | |
| SCHEMBL8575016 | 0.78 | GSTO1 (0.40) | MAPTKDM4ETSHRL3MBTL1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |