Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576504 | 0.86 | CA2 (0.47) | VCAM1ALDH1A1GAASIRT6PDGFRB | |
| SCHEMBL8578530 | 0.85 | MCL1 (0.45) | VCAM1ALDH1A1LMNAGAAHPGD | |
| SCHEMBL29451569 | 0.84 | ALDH1A1 (0.48) | VCAM1ALDH1A1LMNAGAAHPGD | |
| SCHEMBL8572895 | 0.79 | LMNA (0.45) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL8575419 | 0.78 | MAPT (0.47) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL25487018 | 0.77 | PDGFRB (0.51) | VCAM1ALDH1A1LMNAHPGDSIRT6 | |
| SCHEMBL2609104 | 0.77 | TDP1 (0.45) | VCAM1LMNAGAASIRT6MEN1 | |
| SCHEMBL2897667 | 0.77 | PDGFRB (0.50) | VCAM1ALDH1A1LMNAHPGDSIRT6 | |
| SCHEMBL8572740 | 0.77 | GSTO1 (0.42) | ALDH1A1LMNAHPGDKMT2AKDM4E | |
| SCHEMBL15972175 | 0.76 | POLB (0.51) | LMNASIRT6MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |