SCHEMBL9101

SCHEMBL9101

COc1ccccc1[C](c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.58
NPC1 O15118 3/20 0.58
ALDH1A1 P00352 3/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
MAPT P10636 1/20 0.50
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49
HTT P42858 2/20 0.48
CTSD P07339 1/20 0.48
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
TP53 P04637 2/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7952 0.96 RAB9A (0.58) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL8471103 0.87 TP53 (0.53) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL9253579 0.86 NPC1 (0.50) RAB9ANPC1KCNK3KCNK9HTT
SCHEMBL157181 0.86 CA1 (0.60) RAB9ANPC1CA1CA2CA12
SCHEMBL8474959 0.82 MAPT (0.56) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL5486501 0.82 RAB9A (0.57) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL615386 0.82 RAB9A (0.57) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL28674881 0.81 NPC1 (0.61) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL10321909 0.80 KMT2A (0.50) RAB9ANPC1ALDH1A1CA1CA2
SCHEMBL50229 0.79 MAPT (0.64) RAB9ANPC1ALDH1A1MAPTKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11719 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118345073-A GalNAc derivative 詹森生物制药有限公司 2024-07-16 CN claimed
US-12030907-B2 Modified nucleoside phosphoramidites Janssen Biopharma, Inc. (US) 2024-07-09 US claimed
US-20240218365-A1 FORMULATION OF AN ANTISENSE OLIGOMER CONJUGATE THE PROGERIA RESEARCH FOUNDATION, INC. 2024-07-04 US claimed
EP-4392558-A1 ANTISENSE OLIGONUCLEOTIDES HAVING ONE OR MORE ABASIC UNITS Sarepta Therapeutics, Inc. (US) 2024-07-03 EP claimed
EP-4387676-A2 DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES Sarepta Therapeutics, Inc. (US) 2024-06-26 EP claimed
CN-115038790-B Synthesis of 3' -RNA oligonucleotides 阿尔尼拉姆医药品有限公司 2024-06-21 CN claimed
CN-118184532-A Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same 中外制药株式会社 2024-06-14 CN claimed
EP-4380624-A1 MULTIVALENT LIGAND CLUSTERS WITH DIAMINE SCAFFOLD FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2024-06-12 EP claimed
CN-112384520-B Method for producing oligonucleotide compound 日本新药株式会社 2024-06-11 CN claimed
CN-118146284-A GalNAc compound, oligonucleotide conjugate and preparation method thereof 北京悦康科创医药科技股份有限公司 2024-06-07 CN claimed
EP-0177382-A1 Mixed probe and its application, its precursor, its preparation and derivatives containing a modified base for this preparation INSTITUT PASTEUR (FR) 1986-04-09 EP claimed
EP-0135587-A4 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1986-04-02 EP claimed
EP-0135587-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1985-04-03 EP claimed
EP-0121635-A1 3',5',-Diarabinosides, their preparation and their therapeutical application SYNTHELABO (FR) 1984-10-17 EP claimed
EP-0121112-A1 2'-Deoxy-3-phosphonylmethyl nucleosides and method for their preparation Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1984-10-10 EP claimed
WO-1984003285-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS MOLECULAR BIOSYSTEMS INC (US) 1984-08-30 WO claimed
US-4458066-A BOUND TO INORGANIC SUPPORT UNIVERSITY PATENTS, INC. (US) 1984-07-03 US claimed
EP-0058563-A1 Lyophilized phosphorylated nucleosides ens BIO LOGICALS INC. (CA) 1982-08-25 EP claimed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP claimed
EP-0035719-A2 Process for producing modified inorganic polymers, their use in producing polynucleotides, and a reagent useful in these processes UNIVERSITY PATENTS, INC. (US) 1981-09-16 EP claimed