Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101 | 0.86 | RAB9A (0.58) | NPC1RAB9AHPGDKCNK3KCNK9 | |
| SCHEMBL1050768 | 0.84 | CES2 (0.62) | NPC1RAB9ACES2CES1SMN1; SMN2 | |
| SCHEMBL7952 | 0.82 | RAB9A (0.58) | NPC1RAB9AHPGDKCNK3KCNK9 | |
| SCHEMBL21517788 | 0.82 | NPC1 (0.53) | NPC1RAB9ACES2CES1GAA | |
| SCHEMBL8575442 | 0.81 | MAPT (0.57) | NPC1RAB9AGAAHPGDSMN1; SMN2 | |
| SCHEMBL8471103 | 0.75 | TP53 (0.53) | NPC1RAB9AGAAHPGDSMN1; SMN2 | |
| SCHEMBL8474959 | 0.74 | MAPT (0.56) | NPC1RAB9AHPGDSMN1; SMN2KCNK3 | |
| SCHEMBL157181 | 0.74 | CA1 (0.60) | NPC1RAB9AGAASMN1; SMN2KCNK3 | |
| SCHEMBL27956213 | 0.73 | KCNK3 (0.44) | NPC1RAB9ASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL30542256 | 0.73 | CES2 (0.68) | NPC1RAB9ACES2CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5419966-A | Solid support for synthesis of 3'-tailed oligonucleotides | MICROPROBE CORPORATION (US) | 1995-05-30 | — | — | US | claimed |