Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CBX7 | O95931 | 1/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.46 |
| ▸ | CBX8 | Q9HC52 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575593 | 1.00 | CTSS (0.55) | CTSSCTSLCTSKPTPN1IL1RN | |
| SCHEMBL8573218 | 0.91 | MMP8 (0.56) | OPRM1OPRD1OPRK1MMP2MMP9 | |
| SCHEMBL8572721 | 0.91 | MMP8 (0.56) | OPRM1OPRD1OPRK1MMP2MMP9 | |
| SCHEMBL8574997 | 0.89 | CDYL2 (0.46) | CTSSCTSLCTSKPTPN1OPRM1 | |
| SCHEMBL8574999 | 0.89 | CDYL2 (0.46) | CTSSCTSLCTSKPTPN1OPRM1 | |
| SCHEMBL8571238 | 0.86 | PSMB1 (0.61) | CTSSCTSKPTPN1PSMB1PSMB8 | |
| SCHEMBL8571242 | 0.86 | PSMB1 (0.61) | CTSSCTSKPTPN1PSMB1PSMB8 | |
| SCHEMBL8575447 | 0.85 | CTSS (0.53) | CTSSCTSLCTSKMMP8PSMB5 | |
| Hydrochloric Acid SCHEMBL8571569 | 0.85 | OPRD1 (0.52) | CTSSCTSLCTSKPTPN1IL1RN | |
| Hydrochloric Acid SCHEMBL8573389 | 0.85 | OPRD1 (0.52) | CTSSCTSLCTSKPTPN1IL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853713-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5618528-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1997-04-08 | — | — | US | disclosed |
| CN-1146726-A | Block copolymer | NYCOMED IMAGING AS (NO) | 1997-04-02 | — | — | CN | disclosed |
| EP-0748226-A1 | BLOCK COPOLYMERS | NYCOMED IMAGING AS (NO) | 1996-12-18 | — | — | EP | disclosed |