Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189245 | 0.81 | TRPV1 (0.45) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL8668570 | 0.79 | ALDH1A1 (0.43) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL8575856 | 0.78 | AKR1C2 (0.53) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL11832981 | 0.75 | TRPV1 (0.51) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL11615249 | 0.74 | AKR1C2 (0.48) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL5305951 | 0.73 | AKR1C2 (0.49) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL4562595 | 0.72 | AKR1C2 (0.48) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| SCHEMBL8122137 | 0.72 | TRPV1 (0.45) | AKR1C2HDAC1ALDH1A1TRPV1MAPT | |
| Acetic Acid SCHEMBL8733648 | 0.72 | PTPN5 (0.68) | AKR1C2HDAC1ALDH1A1MAPTKDM4E | |
| SCHEMBL11021014 | 0.72 | TRPV1 (0.46) | AKR1C2HDAC1ALDH1A1TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |