Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.42 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106659 | 0.86 | CYP1A2 (0.46) | CYP1A2KLKB1CTSBMMP9DNMT1 | |
| SCHEMBL29921822 | 0.86 | HNF4A (0.51) | AKR1C3ALDH1A1CDC25BCDC25AHSD17B10 | |
| SCHEMBL7198373 | 0.83 | CYP1A2 (0.39) | CYP1A2KLKB1CTSBMMP9DNMT1 | |
| SCHEMBL5134495 | 0.82 | GABRP (0.43) | CYP1A2KLKB1CTSBMMP9DNMT1 | |
| SCHEMBL9547628 | 0.82 | CYP1A2 (0.42) | CYP1A2KLKB1CTSBMMP9DNMT1 | |
| SCHEMBL9547569 | 0.82 | CYP1A2 (0.42) | CYP1A2KLKB1CTSBMMP9DNMT1 | |
| SCHEMBL9547567 | 0.80 | PPARA (0.41) | CYP1A2ALDH1A1ALOX15 | |
| SCHEMBL9547631 | 0.80 | PPARA (0.41) | CYP1A2ALDH1A1ALOX15 | |
| SCHEMBL22989 | 0.79 | CYP1A2 (0.61) | CYP1A2AKR1C3ALDH1A1CDC25BCDC25A | |
| SCHEMBL1988762 | 0.79 | CYP1A2 (0.61) | CYP1A2AKR1C3ALDH1A1CDC25BCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0308270-B1 | Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof | HITACHI CHEMICAL CO LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |
| EP-0308270-A2 | Processes for preparation of polyimide-isoindoquinazoline dione and precursor thereof | Hitachi Chemical Co., Ltd. (JP) | 1989-03-22 | — | — | EP | disclosed |