Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568150 | 0.86 | RAB9A (0.55) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL4100042 | 0.85 | ALDH1A1 (0.45) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL30534176 | 0.85 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL1436251 | 0.85 | RAB9A (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL307126 | 0.84 | CTSD (0.51) | RAB9ASMN1; SMN2NPC1HPGDHTT | |
| SCHEMBL4804041 | 0.83 | KAT6A (0.47) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL4098911 | 0.83 | TAS1R3 (0.49) | ALDH1A1TP53MAPTMAPK1HPGD | |
| SCHEMBL13265349 | 0.83 | ABCB1 (0.46) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL1534517 | 0.82 | CES2 (0.42) | RAB9AALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL8577021 | 0.82 | POLB (0.41) | RAB9AALDH1A1SMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175284-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-06-23 | — | — | US | disclosed |
| US-20160175284-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-06-23 | — | — | US | disclosed |
| US-20160175284-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-06-23 | — | — | US | disclosed |
| WO-1998013341-A1 | HYDROXYBENZOPHENONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175284-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ESR2, GPER1, ESR1 | RAB9A 3980/4885ALDH1A1 1132/4885SMN1; SMN2 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.