Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132366 | 0.82 | NAAA (0.48) | — | |
| SCHEMBL28063604 | 0.75 | CHRNB2 (0.38) | NPC1RAB9AHPGDATML3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL8917318 | 0.74 | CHRNB2 (0.41) | DPP4DPP8LMNAMEN1KMT2A | |
| SCHEMBL20399966 | 0.72 | L3MBTL1 (0.37) | NPC1RAB9AHPGDATML3MBTL1 | |
| SCHEMBL1421475 | 0.72 | POLB (0.45) | DPP4DPP8NPC1RAB9AHPGD | |
| SCHEMBL13731844 | 0.71 | FKBP1A (0.40) | FKBP1ANPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL20819833 | 0.70 | NPC1 (0.40) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL22371739 | 0.70 | NPC1 (0.40) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL14645821 | 0.70 | NPC1 (0.40) | NPC1RAB9AHPGDL3MBTL1MEN1 | |
| SCHEMBL17376785 | 0.70 | NAAA (0.43) | ATML3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5532232-A | INHIBIT THROMBIN INDUCED PLATELET AGGREGATION; FIBRINOGEN ANTICOAGULANTS IN BLOOD | HOFFMANN-LA ROCHE INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5260307-A | Inhibit thrombin-induced platlet aggregation and clotting of fibrogen in plasma | HOFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |