Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NSD2 | O96028 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461137 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ARRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16166578 | 0.77 | TSHR (0.43) | ALDH1A1ARRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8090366 | 0.76 | AR (0.50) | ALDH1A1ARRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9797233 | 0.75 | AR (0.49) | ALDH1A1ARRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5492768 | 0.75 | ALDH1A1 (0.50) | ALDH1A1NSD2RAB9ASMN1; SMN2OPRM1 | |
| SCHEMBL29872795 | 0.74 | MEN1 (0.61) | ALDH1A1ARRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL15766291 | 0.74 | OPRM1 (0.52) | ALDH1A1ARMEN1KMT2AOPRM1 | |
| SCHEMBL432973 | 0.73 | ALOX5 (0.55) | ALDH1A1MEN1KMT2ACYP11B2MAPT | |
| SCHEMBL3936113 | 0.73 | NSD2 (0.74) | ALDH1A1NSD2RAB9ASMN1; SMN2GAA | |
| SCHEMBL11281751 | 0.73 | DRD2 (0.52) | ALDH1A1ARRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789419-A | CARDIOVASCULAR AND BRONCHIAL DISORDERS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0764639-A1 | 4-QUINOLINONE DERIVATIVE OR SALT THEREOF | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-03-26 | — | — | EP | disclosed |