SCHEMBL9797233

SCHEMBL9797233

CC1(Cl)C(=O)N(c2cccc(C(F)(F)F)c2)CC1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.49
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NOTUM Q6P988 1/20 0.43
HTR7 P34969 1/20 0.42
CYP11B2 P19099 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
OPRM1 P35372 1/20 0.41
OPRL1 P41146 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
DHFR P00374 1/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10986755 0.84 AR (0.46) ARMEN1KMT2AHTR7CYP11B2
SCHEMBL10986984 0.79 AR (0.43) ARMEN1KMT2ANOTUMHTR7
SCHEMBL9683395 0.78 AR (0.44) ARMEN1KMT2ANOTUMHTR7
SCHEMBL9735938 0.76 AR (0.42) ARMEN1KMT2ANOTUMKDM4E
SCHEMBL8577305 0.75 ALDH1A1 (0.61) ARMEN1KMT2ACYP11B2ALDH1A1
SCHEMBL10652687 0.74 DRD2 (0.41) ARMEN1KMT2ANOTUMHTR7
SCHEMBL10406730 0.73 NOTUM (0.43) ARMEN1KMT2ANOTUMKDM4E
SCHEMBL10986074 0.72 ALOX5 (0.41) ARMEN1KMT2ANOTUMHTR7
SCHEMBL11079365 0.72 MEN1 (0.44) ARMEN1KMT2AHTR7CYP11B2
SCHEMBL9681581 0.71 HTR7 (0.42) NOTUMHTR7KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1509141-A Herbicides based on substituted aryl ketones �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-06-30 CN claimed
CN-1407854-A N-aryi-uracile-based herbicides BAYER AG (DE) 2003-04-02 CN disclosed
US-5053541-A Condensation of allyamine with m-bromo-trifluoromethyl benzene in presence of nickel compound or complex as catalyst; catalyst selectivity RHONE-POULENC CHIMIE (FR) 1991-10-01 US disclosed