SCHEMBL8577499

SCHEMBL8577499

COCCNC(=O)CN(CCO)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
HCRTR2 O43614 5/20 0.50
HPGD P15428 2/20 0.49
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ACHE P22303 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MAPK8 P45983 1/20 0.45
MAPK10 P53779 1/20 0.45
ALDH1A1 P00352 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14544904 0.81 L3MBTL1 (0.57) MEN1KMT2AHCRTR2LMNAKDM4E
SCHEMBL8575850 0.79 ACHE (0.52) MEN1KMT2AHCRTR2LMNAACHE
SCHEMBL8577501 0.77 HPGD (0.56) MEN1KMT2AHPGDLMNAKDM4E
SCHEMBL39945 0.76 KDM4E (0.56) HPGDLMNAKDM4EACHEAPP
SCHEMBL18379359 0.74 LMNA (0.52) MEN1KMT2ALMNAKDM4EACHE
SCHEMBL12500219 0.74 KDM4E (0.71) MEN1KMT2AHPGDLMNAKDM4E
SCHEMBL3132717 0.74 HTT (0.53) MEN1KMT2ALMNAKDM4EACHE
SCHEMBL14068428 0.73 MEN1 (0.59) MEN1KMT2AHPGDLMNAKDM4E
SCHEMBL8821742 0.72 HPGD (0.44) MEN1KMT2AHCRTR2HPGDKDM4E
Acetic Acid SCHEMBL237341 0.72 HTT (0.58) MEN1KMT2ALMNAKDM4EACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998048844-A2 ION PARIS, METHOD FOR THE PRODUCTION AND USE THEREOF AS CONTRAST AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-11-05 WO disclosed
WO-1998013338-A1 ION PAIRS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS CONTRAST AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-04-02 WO disclosed