Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259019 | 0.95 | LMNA (0.37) | LMNAALDH1A1KMT2AMAPTUSP2 | |
| SCHEMBL8581306 | 0.85 | KDM4E (0.35) | ALDH1A1MAPTHTTKDM4EHPGD | |
| SCHEMBL7202177 | 0.81 | ALDH1A1 (0.42) | LMNAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9412117 | 0.79 | LMNA (0.39) | LMNAALDH1A1KMT2AMAPTUSP2 | |
| SCHEMBL2267166 | 0.69 | LMNA (0.48) | LMNAALDH1A1KMT2AMAPTUSP2 | |
| SCHEMBL7204613 | 0.68 | CYP4F2 (0.46) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11001655 | 0.67 | LMNA (0.44) | LMNAALDH1A1KMT2AMAPTUSP2 | |
| SCHEMBL9254561 | 0.66 | CYP4F2 (0.46) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL22396834 | 0.65 | MRGPRX4 (0.49) | LMNAALDH1A1KMT2AMAPTUSP2 | |
| SCHEMBL11005433 | 0.64 | LMNA (0.41) | LMNAALDH1A1KMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934317-A2 | NOVEL 6 OR 7 SUBSTITUTED ANALOGUES OF SWAINSONINE, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS THERAPEUTIC AGENTS | Glycodesign Inc. (CA) | 1999-08-11 | — | — | EP | disclosed |
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |
| WO-1998014445-A2 | NOVEL 6 OR 7 SUBSTITUTED ANALOGUES OF SWAINSONINE, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS THERAPEUTIC AGENTS | GLYCODESIGN INC. (CA) | 1998-04-09 | — | — | WO | disclosed |
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |