Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 8/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577063 | 0.89 | AR (0.43) | AR | |
| SCHEMBL8573438 | 0.84 | CTSG (0.40) | CHRM2CHRM4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL8575471 | 0.84 | PTGER4 (0.36) | CHRM4ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8571485 | 0.83 | CTSG (0.39) | CHRM2CHRM4HDAC1HDAC6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8573565 | 0.79 | CTSG (0.39) | ALDH1A1TSHR | |
| SCHEMBL8575669 | 0.79 | CTSG (0.39) | CHRM2CHRM4ALDH1A1TSHR | |
| SCHEMBL8571584 | 0.78 | CTSG (0.39) | HDAC1ALDH1A1HPGDTSHR | |
| SCHEMBL8571508 | 0.77 | HTR7 (0.37) | HPGDTSHR | |
| SCHEMBL8575092 | 0.77 | CTSG (0.43) | ALDH1A1TSHR | |
| SCHEMBL8572736 | 0.77 | OPRM1 (0.43) | ALDH1A1HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |