Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.37 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571508 | 0.90 | HTR7 (0.37) | OPRM1OPRL1ELANEMAPTKMT2A | |
| SCHEMBL8575254 | 0.87 | KMT2A (0.37) | OPRM1OPRL1ELANEMAPTKMT2A | |
| SCHEMBL8572795 | 0.86 | ELANE (0.37) | ELANEXIAP | |
| SCHEMBL8573438 | 0.85 | CTSG (0.40) | ELANEMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8571485 | 0.84 | CTSG (0.39) | ELANEMAPTALDH1A1 | |
| SCHEMBL8575660 | 0.80 | GRM5 (0.43) | OPRM1OPRL1 | |
| SCHEMBL8575669 | 0.80 | CTSG (0.39) | ELANEMAPTALDH1A1 | |
| SCHEMBL8573886 | 0.80 | HDAC1 (0.40) | OPRM1OPRL1 | |
| SCHEMBL8571536 | 0.77 | CASP3 (0.38) | MAPTKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL8577922 | 0.77 | CHRM2 (0.41) | ARALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |