Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955591 | 0.76 | ALOX15 (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9545754 | 0.75 | ALDH1A1 (0.53) | TRPV1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL8578419 | 0.75 | TRPV1 (0.51) | TRPV1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL5605077 | 0.74 | AKR1C2 (0.74) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL5270294 | 0.74 | AKR1C2 (0.58) | TRPV1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL8802851 | 0.73 | L3MBTL1 (0.48) | ALDH1A1KDM4EKMT2AMEN1POLB | |
| SCHEMBL8293076 | 0.71 | MTNR1A (0.62) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL4720481 | 0.71 | GAA (0.71) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL8876344 | 0.71 | PTGS2 (0.55) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8978303 | 0.70 | AKR1C2 (0.67) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604253-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS | MERCK FROSST CANADA, INC. (CA) | 1997-02-18 | — | — | US | disclosed |
| WO-1996037469-A1 | N-BENZYLINDOL-3-YL PROPANIC ACID DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1996-11-28 | — | — | WO | disclosed |