Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627691 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2HTT | |
| SCHEMBL6897110 | 0.81 | LMNA (0.49) | SMN1; SMN2CTSLOPRK1TSHR | |
| SCHEMBL8301017 | 0.78 | TLR2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4GGT1 | |
| SCHEMBL2026078 | 0.77 | FOLH1 (0.50) | GGT1SMN1; SMN2HTTITGB3ITGA2B | |
| SCHEMBL2026077 | 0.77 | FOLH1 (0.50) | GGT1SMN1; SMN2HTTITGB3ITGA2B | |
| SCHEMBL6446635 | 0.76 | FOLH1 (0.49) | GGT1SMN1; SMN2HTTITGB3ITGA2B | |
| SCHEMBL6446640 | 0.76 | FOLH1 (0.49) | GGT1SMN1; SMN2HTTITGB3ITGA2B | |
| SCHEMBL31490032 | 0.76 | TGM2 (0.42) | SMN1; SMN2CTSLHTTITGB3ITGA2B | |
| Serine SCHEMBL7381496 | 0.75 | SLC1A3 (0.45) | HTT | |
| SCHEMBL6377386 | 0.75 | TLR2 (0.57) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |
| US-5746995-A | DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |