SCHEMBL8580763

SCHEMBL8580763

CCOC(=O)C1(OC(=O)C(Cl)c2ccccc2Cl)CCC(OC(C)C)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.38
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
USP2 O75604 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM3 P20309 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 2/20 0.33
DEGS1 O15121 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
RAB9A P51151 1/20 0.33
CHRM1 P11229 1/20 0.33
TSHR P16473 2/20 0.33
POLB P06746 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8578903 0.89 OPRM1 (0.34) ALDH1A1SMN1; SMN2OPRM1TSHRPOLB
SCHEMBL8579787 0.80 KMT2A (0.37) ALDH1A1SMN1; SMN2USP2CHRM2CHRM5
SCHEMBL8576984 0.78 OPRM1 (0.35) ALDH1A1SMN1; SMN2MEN1KMT2AGAA
SCHEMBL8578477 0.78 MMP1 (0.35) ALDH1A1SMN1; SMN2OPRM1POLBSLC6A2
SCHEMBL8578898 0.77 KMT2A (0.47) ALDH1A1SMN1; SMN2MEN1KMT2AGAA
SCHEMBL8578564 0.76 OPRM1 (0.33) ALDH1A1SMN1; SMN2OPRM1TSHRPOLB
SCHEMBL8580842 0.74 ADCY8 (0.39) ALDH1A1MEN1KMT2AGAASLC6A2
SCHEMBL8576897 0.74 DEGS1 (0.33) ALDH1A1SMN1; SMN2CHRM2CHRM5MEN1
SCHEMBL8576677 0.74 ACACB (0.35) DEGS1OPRM1
SCHEMBL5322140 0.72 CASP1 (0.57) CASP1ALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5719310-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-02-17 US disclosed
US-5610122-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-11 US disclosed