SCHEMBL8581966

SCHEMBL8581966

CC(C)C[Si](OCOB(O)Oc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ANPEP P15144 1/20 0.31
LAP3 P28838 1/20 0.31
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30
CDK5 Q00535 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7479973 0.76 LMNA (0.30) LMNA
SCHEMBL4851452 0.74 LMNA (0.44) LMNAANPEPLAP3
SCHEMBL18270226 0.72 ALDH1A1 (0.35) LMNA
SCHEMBL20678539 0.70 CA4 (0.39) LMNA
SCHEMBL9175019 0.69 LMNA (0.32) LMNAANPEPLAP3
SCHEMBL2126537 0.68 LTA4H (0.41) LMNA
SCHEMBL28491067 0.67 LTA4H (0.39) LMNA
SCHEMBL15544573 0.66 ALDH1A1 (0.40) LMNA
SCHEMBL8536402 0.66 LMNA (0.35) LMNAANPEPLAP3
SCHEMBL4860138 0.65 LTA4H (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5707987-A BACTERICIDE ANTIBIOTICS BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-01-13 US disclosed