Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 3/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580657 | 0.87 | GAA (0.36) | KMT2ASCN9AATM | |
| SCHEMBL31232485 | 0.78 | SLC6A2 (0.46) | GHSRKDM1ALMNADPP8DPP9 | |
| SCHEMBL30579791 | 0.75 | GHSR (0.36) | GHSRKDM1ALMNAMAPTDPP8 | |
| SCHEMBL8584168 | 0.74 | BUB1 (0.32) | GHSRSCN9A | |
| SCHEMBL8997716 | 0.74 | GHSR (0.33) | GHSRPRMT5WDR77LMNAL3MBTL1 | |
| SCHEMBL8997695 | 0.69 | P2RY1 (0.37) | — | |
| SCHEMBL8581721 | 0.68 | GHSR (0.48) | KMT2AGHSRXIAPPRMT5WDR77 | |
| SCHEMBL8997591 | 0.67 | GHSR (0.36) | KMT2AGHSRLMNAATM | |
| SCHEMBL8613152 | 0.67 | GHSR (0.36) | KMT2AGHSRLMNAATM | |
| SCHEMBL9874570 | 0.65 | GHSR (0.43) | GHSRKDM1ADPP8DPP9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |