Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584095 | 0.87 | KMT2A (0.33) | KMT2AATMSCN9A | |
| SCHEMBL8580708 | 0.76 | GHSR (0.43) | GAABACE1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31232485 | 0.76 | SLC6A2 (0.46) | CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8997611 | 0.76 | RPS6KA1 (0.34) | GAABACE1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30579791 | 0.73 | GHSR (0.36) | — | |
| SCHEMBL8580711 | 0.72 | SYK (0.42) | KMT2AATM | |
| SCHEMBL8997591 | 0.70 | GHSR (0.36) | BACE1KMT2AATM | |
| SCHEMBL8613152 | 0.70 | GHSR (0.36) | BACE1KMT2AATM | |
| SCHEMBL8582291 | 0.67 | SYK (0.42) | ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL8997715 | 0.67 | CPB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |