Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 6/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997695 | 0.91 | P2RY1 (0.37) | KDM4E | |
| SCHEMBL8997611 | 0.87 | RPS6KA1 (0.34) | GHSR | |
| SCHEMBL8997631 | 0.85 | SYK (0.35) | GHSRPRMT5WDR77IDO1CASP3 | |
| SCHEMBL8997594 | 0.84 | SYK (0.40) | LMNA | |
| SCHEMBL8997715 | 0.82 | CPB2 (0.31) | GHSR | |
| SCHEMBL8997810 | 0.78 | P2RY1 (0.39) | KDM4E | |
| SCHEMBL8997761 | 0.78 | GHSR (0.33) | GHSR | |
| SCHEMBL8997804 | 0.78 | P2RY1 (0.37) | KDM4E | |
| SCHEMBL8584095 | 0.74 | KMT2A (0.33) | GHSRPRMT5WDR77LMNAL3MBTL1 | |
| SCHEMBL8997625 | 0.74 | GHSR (0.37) | GHSRPRMT5WDR77LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |