Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584852 | 0.80 | QDPR (0.50) | ALOX15KDM4ELMNAHTR6HTR1A | |
| SCHEMBL8583003 | 0.78 | SIGMAR1 (0.52) | DRD4CYP3A4TSHRTDP1HTR1A | |
| SCHEMBL14385616 | 0.76 | DRD4 (0.50) | ALOX15KDM4ELMNAHTR6DRD4 | |
| SCHEMBL10241131 | 0.73 | KDM4E (0.56) | ALOX15KDM4ELMNADRD4HTR1A | |
| SCHEMBL14144244 | 0.73 | SIGMAR1 (0.54) | ALOX15KDM4ELMNAHTR6DRD4 | |
| SCHEMBL8610238 | 0.72 | HTR1F (0.42) | ALOX15KDM4ELMNAHTR6HTR1F | |
| SCHEMBL25124915 | 0.70 | SIGMAR1 (0.55) | ALOX15KDM4ELMNAHTR6DRD4 | |
| SCHEMBL7910148 | 0.70 | NPSR1 (0.60) | ALOX15KDM4ELMNATDP1DRD2 | |
| SCHEMBL10241118 | 0.70 | SIGMAR1 (0.57) | HTR6TDP1HTR1ADRD2 | |
| SCHEMBL2934369 | 0.70 | KDM4E (0.70) | ALOX15KDM4ELMNAHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |