Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484775 | 0.83 | SIGMAR1 (0.66) | SIGMAR1DRD2DRD4DRD3PARP1 | |
| SCHEMBL8674007 | 0.79 | SIGMAR1 (0.48) | SIGMAR1DRD2DRD4DRD3PARP1 | |
| SCHEMBL8585451 | 0.78 | ALOX15 (0.48) | DRD2DRD4DRD3HTR1ACYP3A4 | |
| SCHEMBL8610590 | 0.74 | SIGMAR1 (0.50) | SIGMAR1DRD2DRD4DRD3PARP1 | |
| Hydrochloric Acid SCHEMBL11318644 | 0.73 | HTR1A (0.78) | SIGMAR1DRD2HTR1ATMEM97 | |
| SCHEMBL11329993 | 0.73 | HTR1A (0.78) | SIGMAR1DRD2HTR1ATMEM97 | |
| SCHEMBL8610861 | 0.73 | L3MBTL1 (0.44) | SIGMAR1DRD2DRD4DRD3PARP1 | |
| SCHEMBL8584852 | 0.73 | QDPR (0.50) | HTR1A | |
| SCHEMBL8194797 | 0.72 | S1PR1 (0.64) | SIGMAR1DRD2DRD4DRD3S1PR1 | |
| SCHEMBL9501239 | 0.72 | SIGMAR1 (0.55) | SIGMAR1DRD2DRD4DRD3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |