Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.53 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584661 | 0.82 | HTR1F (0.57) | HTR1FCCNA2CDK2CCNA1HTR1D | |
| SCHEMBL8583773 | 0.82 | HTR1F (0.57) | HTR1FESR1HTR1DHTR1BHTR1A | |
| SCHEMBL8584823 | 0.81 | P2RY14 (0.41) | HTR1FP2RY14HTR1DHTR1BHTR1A | |
| SCHEMBL28778473 | 0.79 | HDAC3 (0.61) | — | |
| SCHEMBL8584849 | 0.78 | HTR1F (0.60) | HTR1FHTR1DHTR1BHTR1A | |
| Hydrochloric Acid SCHEMBL28778472 | 0.78 | HDAC3 (0.59) | — | |
| SCHEMBL8586155 | 0.77 | HTR1F (0.45) | HTR1FP2RY14 | |
| SCHEMBL8586465 | 0.76 | HSD17B10 (0.46) | HTR1FHTR1DHTR1BHTR1A | |
| SCHEMBL8583266 | 0.76 | RAB9A (0.44) | HTR1FHTR1DHTR1BHTR1A | |
| SCHEMBL8636423 | 0.73 | HTR1F (0.54) | HTR1FP2RY14HTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |