Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584823 | 0.79 | P2RY14 (0.41) | RAB9ANPC1HPGDCASP3SENP8 | |
| SCHEMBL8583266 | 0.76 | RAB9A (0.44) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8585459 | 0.76 | HTR1F (0.53) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL8586155 | 0.75 | HTR1F (0.45) | HTR1F | |
| SCHEMBL359241 | 0.72 | RAB9A (0.74) | HSD17B10RAB9ANPC1MEN1KMT2A | |
| SCHEMBL7008621 | 0.70 | HTR1F (0.77) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL5867599 | 0.69 | HSD17B10 (0.52) | HSD17B10RAB9ANPC1MEN1KMT2A | |
| SCHEMBL229300 | 0.69 | ALDH1A1 (0.51) | HSD17B10RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11311286 | 0.68 | RAB9A (0.58) | HSD17B10RAB9ANPC1MEN1KMT2A | |
| Bromide SCHEMBL10964629 | 0.68 | ALDH1A1 (0.50) | HSD17B10RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |