Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584756 | 0.82 | HTR1D (0.51) | HTR1FQDPRSLC18A3 | |
| SCHEMBL8585459 | 0.77 | HTR1F (0.53) | HTR1FP2RY14 | |
| SCHEMBL8584823 | 0.75 | P2RY14 (0.41) | HTR1FCDK1CDK5P2RY14 | |
| SCHEMBL8586465 | 0.75 | HSD17B10 (0.46) | HTR1F | |
| SCHEMBL8583266 | 0.75 | RAB9A (0.44) | HTR1F | |
| SCHEMBL10127506 | 0.73 | NAMPT (0.59) | NAMPTSLC18A3 | |
| SCHEMBL4098389 | 0.72 | HTR2C (0.54) | HTR2C | |
| SCHEMBL12975618 | 0.71 | GSK3B (0.42) | HTR1FP2RY14TLR9TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL3337152 | 0.71 | HTR2C (0.55) | HTR2C | |
| SCHEMBL12975614 | 0.70 | TLR9 (0.60) | HTR1FQDPRTLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |