Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583210 | 0.85 | HTR1A (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8585768 | 0.82 | NPC1 (0.52) | RAB9ANPC1ALDH1A1TP53KDM4E | |
| SCHEMBL8611280 | 0.80 | OPRM1 (0.49) | — | |
| SCHEMBL8586465 | 0.76 | HSD17B10 (0.46) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL8585459 | 0.76 | HTR1F (0.53) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL8586155 | 0.75 | HTR1F (0.45) | HTR1F | |
| SCHEMBL8584823 | 0.74 | P2RY14 (0.41) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL1844542 | 0.71 | ALDH1A1 (0.72) | NPC1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7011205 | 0.70 | HTR1F (0.77) | HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL11463346 | 0.67 | ALDH1A1 (0.57) | NPC1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |