Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 10/20 | 0.45 |
| ▸ | MDM4 | O15151 | 5/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233103 | 0.79 | MEN1 (0.45) | MCL1MDM2MDM4ALOX15NPC1 | |
| SCHEMBL8587962 | 0.77 | ALDH1A1 (0.45) | ALOX15ALDH1A1 | |
| SCHEMBL7564714 | 0.76 | ALOX15 (0.43) | MCL1ALOX15ALDH1A1HPGD | |
| SCHEMBL6233791 | 0.75 | NR4A2 (0.52) | ALOX15 | |
| SCHEMBL27008293 | 0.74 | CTSV (0.54) | CTSVCTSLALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL6230583 | 0.73 | NR4A2 (0.52) | ALOX15 | |
| SCHEMBL6169184 | 0.73 | MCL1 (0.51) | MCL1MDM2MDM4ALOX15 | |
| SCHEMBL27531815 | 0.71 | MAOB (0.47) | MCL1MDM2MDM4ALOX15SMN1; SMN2 | |
| SCHEMBL27142999 | 0.71 | CTSV (0.53) | CTSVCTSLALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL6169364 | 0.70 | PTGS2 (0.54) | MCL1MDM2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849920-A | Substituted trifluoromethylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5750705-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| US-5744471-A | NERVOUS SYSTEM DISORDERS | ZENECA LIMITED (GB) | 1998-04-28 | — | — | US | disclosed |