Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 2/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764898 | 0.88 | LMNA (0.64) | LMNASMN1; SMN2 | |
| SCHEMBL14181569 | 0.88 | LMNA (0.41) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7076147 | 0.87 | LMNA (0.39) | LMNA | |
| SCHEMBL7581409 | 0.86 | LMNA (0.42) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7581413 | 0.86 | LMNA (0.42) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL7581432 | 0.85 | LMNA (0.41) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6879887 | 0.85 | LMNA (0.40) | LMNATSHRKLK7 | |
| SCHEMBL5356462 | 0.85 | LMNA (0.40) | LMNATSHRKLK7 | |
| Hydrochloric Acid SCHEMBL7071547 | 0.85 | LMNA (0.41) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5482338 | 0.85 | LMNA (0.40) | LMNATSHRKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10007636-A | — | — | None | — | — | JP | disclosed |
| JP-H107636-A | PRODUCTION OF INTERMEDIATE USEFUL FOR SYNTHESIZING IODIDE CONTRAST MEDIUM | ZAMBON GROUP SPA | 1998-01-13 | — | — | JP | disclosed |