Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL28880704 | 0.92 | PRCP (0.37) | KMT2APRCP | |
| Arginine SCHEMBL4223569 | 0.92 | PRCP (0.33) | ALOX15BLMPMP22KMT2APRCP | |
| Arginine SCHEMBL27801173 | 0.91 | PRCP (0.30) | PRCP | |
| Arginine SCHEMBL4398586 | 0.90 | PRCP (0.36) | PRCP | |
| Arginine SCHEMBL28755791 | 0.89 | ALOX15 (0.35) | ALOX15BLMPMP22KMT2APRCP | |
| Glutamine SCHEMBL27823468 | 0.89 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2A | |
| Arginine SCHEMBL16581528 | 0.89 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2APRCP | |
| Arginine SCHEMBL8587129 | 0.88 | ALOX15 (0.31) | ALOX15BLMPMP22KMT2APRCP | |
| Arginine SCHEMBL4396599 | 0.88 | PRCP (0.35) | PRCP | |
| Arginine SCHEMBL29141605 | 0.88 | KDM1A (0.34) | ALOX15BLMPMP22KMT2APRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877811-A1 | MUTATED PRENYL DIPHOSPHATE SYNTHASES | Toyota Jidosha Kabushiki Kaisha (JP) | 1998-11-18 | — | — | EP | disclosed |
| WO-1998020138-A1 | MUTATED PRENYL DIPHOSPHATE SYNTHASES | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 1998-05-14 | — | — | WO | disclosed |