Arginine

SCHEMBL8587378

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1ccccc1.N=C(N)NCCC[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](Cc1ccc(OC(=O)[C@@H](N)Cc2c[nH]cn2)cc1)C(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	4/20	0.37

▸	GLP1R	P43220	6/20	0.33

▸	NPY4R	P50391	4/20	0.33

▸	NPY1R	P25929	3/20	0.33

▸	PTH1R	Q03431	2/20	0.33

▸	KEAP1	Q14145	1/20	0.33

▸	NPY2R	P49146	2/20	0.32

▸	NPY5R	Q15761	2/20	0.32

▸	MC4R	P32245	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Tyrosine SCHEMBL8587374	0.90	NPY4R (0.40)	APLNRGLP1RNPY4RNPY1RNPY2R
Tyrosine SCHEMBL27448866	0.90	NPY4R (0.39)	APLNRGLP1RNPY4RNPY1RNPY2R
Cystine SCHEMBL27543315	0.88	APLNR (0.38)	APLNRGLP1RPTH1RKEAP1
Histidine SCHEMBL4778276	0.87	NPY4R (0.40)	NPY4RNPY1RNPY2RNPY5RMC4R
SCHEMBL17363643	0.86	FNTA (0.39)	APLNRNPY4RNPY1RNPY2RNPY5R
Tyrosine SCHEMBL27677075	0.86	NPY4R (0.43)	GLP1RNPY4RNPY1RNPY2RNPY5R
Tyrosine SCHEMBL27506997	0.86	NPY4R (0.39)	APLNRGLP1RNPY4RNPY1RKEAP1
Tyrosine SCHEMBL27431939	0.85	NPY4R (0.42)	GLP1RNPY4RNPY1RNPY2RNPY5R
Arginine SCHEMBL7211146	0.85	GLP1R (0.35)	APLNRGLP1RPTH1R
Tryptophan SCHEMBL27389650	0.84	TUBB4A (0.44)	GLP1RPTH1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
JP-10245399-A	—	—	None	—	—	JP	disclosed
JP-H10245399-A	NEW LECTIN, ITS PRODUCTION AND USE	TEIKA CORP	1998-09-14	—	—	JP	disclosed