Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.40 |
| ▸ | NPY1R | P25929 | 6/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL8318272 | 0.90 | ITGB3 (0.43) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| SCHEMBL10613823 | 0.90 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| Histidine SCHEMBL2330373 | 0.89 | SLC7A5 (0.41) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| Histidine SCHEMBL2331922 | 0.88 | NPY4R (0.37) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| Arginine SCHEMBL8587378 | 0.87 | APLNR (0.37) | NPY4RNPY1RNPY2RNPY5RMC4R | |
| Arginine SCHEMBL8744510 | 0.87 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| Arginine SCHEMBL8315939 | 0.86 | SLC7A5 (0.40) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| Arginine SCHEMBL8317787 | 0.86 | SLC7A5 (0.40) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| SCHEMBL17363643 | 0.86 | FNTA (0.39) | NPY4RNPY1RNPY2RNPY5RITGB3 | |
| Arginine SCHEMBL29052768 | 0.85 | NPY4R (0.39) | NPY4RNPY1RNPY2RNPY5RTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076097-B1 | METHOD FOR CONTROLLING CLEAVAGE BY OmpT PROTEASE | ASUBIO PHARMA CO LTD (JP) | 2008-11-12 | — | — | EP | disclosed |
| US-7344856-B1 | Method of controlling cleavage by OmpT protease | ASUBIO PHARMA CO. LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| EP-1076097-A1 | METHOD FOR CONTROLLING CLEAVAGE BY OmpT PROTEASE | SUNTORY LIMITED (JP) | 2001-02-14 | — | — | EP | disclosed |