SCHEMBL17363643

SCHEMBL17363643

CSCC[C@H](N)C(=O)Oc1ccc(C[C@H](N)C(=O)O)cc1.N=C(N)NCCC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1c[nH]cn1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FNTA P49354 8/20 0.39
FNTB P49356 8/20 0.39
PGGT1B P53609 8/20 0.39
SLC7A5 Q01650 1/20 0.35
NPY4R P50391 7/20 0.34
NPY1R P25929 5/20 0.34
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33
NPY2R P49146 4/20 0.32
NPY5R Q15761 4/20 0.32
APLNR P35414 1/20 0.32
CTSL P07711 2/20 0.32
CTSS P25774 2/20 0.32
CTSK P43235 2/20 0.32
CTSH P09668 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL2330373 0.91 SLC7A5 (0.41) FNTAFNTBPGGT1BSLC7A5NPY4R
Arginine SCHEMBL8315939 0.90 SLC7A5 (0.40) FNTAFNTBPGGT1BSLC7A5NPY4R
Arginine SCHEMBL8317787 0.90 SLC7A5 (0.40) FNTAFNTBPGGT1BSLC7A5NPY4R
Arginine SCHEMBL8587378 0.86 APLNR (0.37) NPY4RNPY1RNPY2RNPY5RAPLNR
Histidine SCHEMBL2331922 0.86 NPY4R (0.37) FNTAFNTBPGGT1BSLC7A5NPY4R
Histidine SCHEMBL4778276 0.86 NPY4R (0.40) SLC7A5NPY4RNPY1RITGB3ITGA2B
Arginine SCHEMBL8318272 0.86 ITGB3 (0.43) SLC7A5NPY4RNPY1RITGB3ITGA2B
Valine SCHEMBL16992661 0.86 NPY4R (0.35) SLC7A5NPY4RNPY1RITGB3ITGA2B
Arginine SCHEMBL23362144 0.85 FNTA (0.37) FNTAFNTBPGGT1BAPLNRCTSL
Arginine SCHEMBL8512347 0.85 FNTA (0.37) FNTAFNTBPGGT1BAPLNRCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795551-B2 Tetrapeptides and a method of use as an antioxidant L'OREAL (FR) 2017-10-24 US disclosed
US-9624265-B2 Short peptides and a method of use as an antioxidant L'OREAL (FR) 2017-04-18 US disclosed
US-9464111-B2 Short peptides and a method of use as an antioxidant L'OREAL (FR) 2016-10-11 US disclosed
US-20160184208-A1 SHORT PEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT L'OREAL (FR) 2016-06-30 US disclosed
US-20150376234-A1 SHORT PEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT L'OREAL (FR) 2015-12-31 US disclosed
US-20150374606-A1 TETRAPEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT L'OREAL (FR) 2015-12-31 US disclosed
WO-2015200656-A1 SHORT PEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT L'OREAL (FR) 2015-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376234-A1 SHORT PEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT LPO, CAT, GPX4 FNTA 4118/4885FNTB 3459/4885PGGT1B 4544/4885
US-20160184208-A1 SHORT PEPTIDES AND A METHOD OF USE AS AN ANTIOXIDANT CUTA, KRT18, LPO FNTA 4769/4885FNTB 4078/4885PGGT1B 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.